The closing pair is the final base pair in a stack. The identity of the closing base pair often influences the energy of the loop that follows it. Loop energy is lowest with GC closing pairs.

Ad blocker interference detected!

Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers

Wikia is not accessible if you’ve made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected.