Design with stack caps. Stable.

"Stack caps" are closing GC pairs. Loop energy is lowest when the closing base pair is a GC pair. Puzzles with restrictions on the number of GC pairs usually require the strategic use of stack caps. Most successful player designs in lab also make use of stack caps.

Ad blocker interference detected!

Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers

Wikia is not accessible if you’ve made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected.